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Livres
Articles (87)
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Membrane transporters in drug development

Giacomini, Kathleen M., Huang, Shiew-Mei, Tweedie, Donald J., Benet, Leslie Z., Brouwer, Kim L.R., Chu, Xiaoyan, Dahlin, Amber, Evers, Raymond, Fischer, Volker, Hillgren, Kathleen M.

Journal:

Nature Reviews Drug Discovery

Année:

2010

Langue:

english

Fichier:

PDF, 646 KB

english, 2010

Analysis of laminated beams with a layer-wise constant shear theory

Julio F. Davalos, Youngchan Kim, Ever J. Barbero

Journal:

Composite Structures

Année:

1994

Langue:

english

Fichier:

PDF, 864 KB

english, 1994

Delamination buckling of FRP layer in laminated wood beams

Youngchan Kim, Julio F. Davalos, Ever J. Barbero

Journal:

Composite Structures

Année:

1997

Langue:

english

Fichier:

PDF, 908 KB

english, 1997

Selective targeting of the nuclear factor-κB pathway enhances tumor necrosis factor–related apoptosis-inducing ligand-mediated pancreatic cancer cell death

Thomas, Robert P, Farrow, Buckminster J, Kim, Sunghoon, May, Michael J, Hellmich, Mark R, Evers, B.Mark

Journal:

Surgery

Année:

2002

Langue:

english

Fichier:

PDF, 221 KB

english, 2002

A protocol of a randomized controlled multicenter trial for surgical treatment of lumbar spondylolisthesis: the Lumbar Interbody Fusion Trial (LIFT)

de Kunder, Suzanne L., Rijkers, Kim, van Kuijk, Sander M. J., Evers, Silvia M. A. A., de Bie, Rob A., van Santbrink, Henk

Journal:

BMC Musculoskeletal Disorders

Année:

2016

Langue:

english

Fichier:

PDF, 576 KB

english, 2016

Neurotensin Receptor 3/Sortilin Contributes to Tumorigenesis of Neuroendocrine Tumors Through Augmentation of Cell Adhesion and Migration

Kim, Ji Tae, Napier, Dana L., Weiss, Heidi L., Lee, Eun Y., Townsend, Courtney M., Evers, B. Mark

Journal:

Neoplasia

Année:

2018

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2018

Automatic temporal ranking of children’s engagement levels using multi-modal cues

Kim, Jaebok, Truong, Khiet P., Evers, Vanessa

Journal:

Computer Speech & Language

Année:

2018

Langue:

english

Fichier:

PDF, 1.59 MB

english, 2018

[IEEE 2017 Seventh International Conference on Affective Computing and Intelligent Interaction (ACII) - San Antonio, TX, USA (2017.10.23-2017.10.26)] 2017 Seventh International Conference on Affective Computing and Intelligent Interaction (ACII) - Learning spectro-temporal features with 3D CNNs for speech emotion recognition

Kim, Jaebok, Truong, Khiet P., Englebienne, Gwenn, Evers, Vanessa

Année:

2017

Langue:

english

Fichier:

PDF, 930 KB

english, 2017

Disease-Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of Drugs: A White Paper from the International Transporter Consortium

Evers, Raymond, Piquette-Miller, Micheline, Polli, Joseph W., Russel, Frans G. M., Sprowl, Jason A., Tohyama, Kimio, Ware, Joseph A., de Wildt, Saskia N., Xie, Wen, Brouwer, Kim L. R.

Journal:

Clinical Pharmacology & Therapeutics

Année:

2018

Langue:

english

Fichier:

PDF, 2.37 MB

english, 2018

Sa1620 - Mitochondrial 3-Hydroxy-3-Methylglutaryl-Coa Synthase 2 (Hmgcs2) is a Target of Wnt/β-Catenin Signaling in Human Colorectal Cancer Cells

Kim, Ji Tae, Wang, Qingding, Weiss, Heidi L., Evers, B. Mark

Journal:

Gastroenterology

Année:

2018

Langue:

english

Fichier:

PDF, 128 KB

english, 2018

Mo1862 - Outcomes of Dose Escalation and Drug Level Monitoring in Patients with Inflammatory Bowel Disease Treated with Vedolizumab

Scoville, Elizabeth A., Izmaylov, Michelle L., Bennett, Audrey, Evers, Lauren, Annis, Kim, Garrett, Ailish, Duley, Caroline, Adams, Dawn W., Dalal, Robin L., Beaulieu, Dawn, Schwartz, David A., Horst,

Journal:

Gastroenterology

Année:

2018

Langue:

english

Fichier:

PDF, 846 KB

english, 2018

Inhibition of neurotensin-induced pancreatic carcinoma growth by a nonpeptide neurotensin receptor antagonist, SR48692

Kazuhiro Iwase, B. Mark Evers, Mark R. Hellmich, Hong Jin Kim, Shunichi Higashide, Danielle Gully, James C. Thompson, Courtney M. Townsend Jr.

Journal:

Cancer

Année:

1997

Langue:

english

Fichier:

PDF, 192 KB

english, 1997

Geldanamycin decreases Raf-1 and Akt levels and induces apoptosis in neuroblastomas

Sunghoon Kim, Junghee Kang, Wanqin Hu, B. Mark Evers, Dai H. Chung

Journal:

International Journal of Cancer

Année:

2003

Langue:

english

Fichier:

PDF, 327 KB

english, 2003

A layerwise beam element for analysis of frames with laminated sections and flexible joints

Julio F. Davalos, Youngchan Kim, Ever J. Barbero

Journal:

Finite Elements in Analysis and Design

Année:

1995

Langue:

english

Fichier:

PDF, 691 KB

english, 1995

Protocol for Translabial 3D-Ultrasonography for diagnosing levator defects (TRUDIL): a multicentre cohort study for estimating the diagnostic accuracy of translabial 3D-ultrasonography of the pelvic floor as compared to MR imaging

Kim JB Notten, Mirjam Weemhoff, Kirsten B Kluivers, Karlijn J Schweitzer, Femke Mulder, Jaap Stoker, Regina GH Beets-Tan, Jurgen J Futterer, Roy FA Vliegen, Johannes LH Evers, Gerold Link, Martin GM B

Journal:

BMC Women's Health

Année:

2011

Langue:

english

Fichier:

PDF, 198 KB

english, 2011

Cost-effectiveness of ward-based pharmacy care in surgical patients: protocol of the SUREPILL (Surgery & Pharmacy In Liaison) study

Monica de Boer, Maya A Ramrattan, Jordy JS Kiewiet, Eveline B Boeker, Kim B Gombert-Handoko, Nicolette AEM van Lent-Evers, Paul F Kuks, Marcel GW Dijkgraaf, Marja A Boermeester, Loraine Lie-A-Huen, Th

Journal:

BMC Health Services Research

Année:

2011

Langue:

english

Fichier:

PDF, 450 KB

english, 2011

A functional in vitro model to examine signaling mechanisms in gastrin-mediated human cell growth

Hong Jin Kim, B. Mark Evers, Nitesh A. Banker, Mark R. Hellmich, Courtney M. Towsend

Journal:

Journal of Gastrointestinal Surgery

Année:

1997

Langue:

english

Fichier:

PDF, 636 KB

english, 1997

Novel Expression and Regulation of Gastrin Gene in Human Ovarian Cancer Cell Line, SW626

Hong Jin Kim, B. Mark Evers, Nitesh A. Banker, George H. Greeley, Mark R. Hellmich, James C. Thompson, Courtney M. Townsend

Journal:

Digestive Diseases and Sciences

Année:

1998

Langue:

english

Fichier:

PDF, 506 KB

english, 1998

Ets transcriptional regulation of gastrin-releasing peptide receptor in neuroblastomas

Jingbo Qiao, Jeremy Cree, Junghee Kang, Sunghoon Kim, B.Mark Evers, Dai H. Chung

Journal:

Surgery

Année:

2004

Langue:

english

Fichier:

PDF, 177 KB

english, 2004

Indirect inhibitory effect of a neurotensin receptor antagonist on human colon cancer (LoVo) growth

K. Iwase, B.M. Evers, M.R. Hellmich, H.J. Kim, S. Higashide, D. Gully, C.M. Townsend Jr

Journal:

Surgical Oncology

Année:

1996

Langue:

english

Fichier:

PDF, 1.02 MB

english, 1996

Molecular mechanisms contributing to oxidative injury in intestinal epithelial cells

Dai H Chung, Richard T Ethridge, Sunghoon Kim, Ambrosio Hernandez, Mark Evers

Journal:

Journal of the American College of Surgeons

Année:

2000

Langue:

english

Fichier:

PDF, 188 KB

english, 2000

Expression and functional regulation of the gastrin-releasing peptide (GRP) receptor in the neuroblastoma cell line IMR-32

Sunghoon Kim, Dai H Chung, Juan Escalon, Jell Hsieh, Mark R Hellmich, B.Mark Evers

Journal:

Journal of the American College of Surgeons

Année:

2000

Langue:

english

Fichier:

PDF, 238 KB

english, 2000

Activation of NF-κB Binding in HT-29 Colon Cancer Cells by Inhibition of Phosphatidylinositol 3-Kinase

Qingding Wang, Sunghoon Kim, Xiaofu Wang, B.Mark Evers

Journal:

Biochemical and Biophysical Research Communications

Année:

2000

Langue:

english

Fichier:

PDF, 124 KB

english, 2000

Sialoglycoconjugate changes during 2-acetylaminofluorene-induced hepatocarcinogenesis in the rat

Kim E. Creek, Vivian P. Walter, David Evers, Emily Yeo, William L. Elliott, Peter F. Heinstein, Dorothy M. Morré, D.James Morré

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Année:

1984

Langue:

english

Fichier:

PDF, 761 KB

english, 1984

Interferon-γ induces caspase-8 in neuroblastomas without affecting methylation of caspase-8 promoter

Sunghoon Kim, Junghee Kang, B.Mark Evers, Dai H. Chung

Journal:

Journal of Pediatric Surgery

Année:

2004

Langue:

english

Fichier:

PDF, 318 KB

english, 2004

Phosphatidylinositol 3-kinase inhibition down-regulates survivin and facilitates TRAIL-mediated apoptosis in neuroblastomas

Sunghoon Kim, Junghee Kang, Jingbo Qiao, Robert P. Thomas, B.Mark Evers, Dai H. Chung

Journal:

Journal of Pediatric Surgery

Année:

2004

Langue:

english

Fichier:

PDF, 176 KB

english, 2004

Bombesin-mediated AP-1 activation in a human gastric cancer (SIIA)

Hong Jin Kim, B. Mark Evers, Yu Guo, Nitesh A. Banker, Mark R. Hellmich, Courtney M. Townsend Jr.

Journal:

Surgery

Année:

1996

Langue:

english

Fichier:

PDF, 2.32 MB

english, 1996

Src-mediated activation of the human neurotensin/neuromedin N promoter

Nitesh A Banker, Mark R Hellmich, Hong Jin Kim, Courtney M Townsend Jr., B.Mark Evers

Journal:

Surgery

Année:

1997

Langue:

english

Fichier:

PDF, 698 KB

english, 1997

Butyrate sensitizes human colon cancer cells to TRAIL-mediated apoptosis

Ambrosio Hernandez, Robert Thomas, Farin Smith, Jennie Sandberg, Sunghoon Kim, Dai H. Chung, B.Mark Evers

Journal:

Surgery

Année:

2001

Langue:

english

Fichier:

PDF, 706 KB

english, 2001

Regulation of growth of human gastric cancer by gastrin and glycine- extended progastrin

K Iwase, BM Evers, MR Hellmich, YS Guo, S Higashide, HJ Kim, CM Townsend Jr

Journal:

Gastroenterology

Année:

1997

Langue:

english

Fichier:

PDF, 342 KB

english, 1997

Inhibition of gastric cancer by camptothecin involves apoptosis and multiple cellular pathways

David A. Litvak, Harry T. Papaconstantinou, Kevin O. Hwang, Mimi Kim, B.Mark Evers, Courtney M. Townsend Jr

Journal:

Surgery

Année:

1999

Langue:

english

Fichier:

PDF, 202 KB

english, 1999

Induction of TRAIL expression in fetal intestinal cells associated with P13-kinase inhibition and differentiation

Qinding Wang, Xiaofu Wang, Sunhoon Kim, B. Mark Evers

Journal:

Gastroenterology

Année:

2001

Langue:

english

Fichier:

PDF, 153 KB

english, 2001

Targeting PI3K/AKT Pathway is an Effective Strategy for the Treatment of Neuroendocrine Tumors Harboring PIK3CA Mutations

Jun Song, Jing Li, Ji Tae Kim, Heidi Weiss, Courtney M. Townsend, B.M. Evers

Journal:

Gastroenterology

Année:

2011

Langue:

english

Fichier:

PDF, 122 KB

english, 2011

956 The Wnt Signaling Pathway is Deregulated in Human Neuroendocrine Tumor Cells by Epigenetic Silencing of Sfrp-1 and WIF-1

Ji Tae Kim, Jing Li, Eun Ryoung Jang, Piotr Rychahou, Heidi L. Weiss, Courtney M. Townsend, Chunming Liu, B. Mark Evers

Journal:

Gastroenterology

Année:

2012

Langue:

english

Fichier:

PDF, 64 KB

english, 2012

Inhibition of the phosphatidylinositol 3-kinase pathway contributes to HT29 and Caco-2 intestinal cell differentiation

Qingding Wang, Xiaofu Wang, Ambrosio Hernandez, Sunghoon Kim, B. Mark Evers

Journal:

Gastroenterology

Année:

2001

Langue:

english

Fichier:

PDF, 625 KB

english, 2001

PTEN and TNF-α regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-κB–dependent pathway

Sunghoon Kim, Claire Domon-Dell, Qingding Wang, Dai H. Chung, Antonio Di Cristofano, Pier Paolo Pandolfi, Jean-Noel Freund, B.Mark Evers

Journal:

Gastroenterology

Année:

2002

Langue:

english

Fichier:

PDF, 842 KB

english, 2002

Paraffin Embedding Contributes to RNA Aggregation, Reduced RNA Yield, and Low RNA Quality

Evers, David L., He, Junkun, Kim, Yeon Ho, Mason, Jeffrey T., O'Leary, Timothy J.

Journal:

The Journal of Molecular Diagnostics

Année:

2011

Langue:

english

Fichier:

PDF, 942 KB

english, 2011

658 Neurotensin, a Novel Target of Wnt/β-Catenin Pathway, Promotes Growth of Neuroendocrine Tumor Cells

Kim, Ji Tae, Liu, Chunming, Townsend, Courtney M., Evers, B. Mark

Journal:

Gastroenterology

Année:

2014

Langue:

english

Fichier:

PDF, 58 KB

english, 2014

Mo1625 Co-Targeting of the PI3K and RAS Pathways for the Treatment of Carcinoid Tumors

Valentino, Joseph, Li, Jing, Kim, Ji Tae, Song, Jun, Mustain, W.C., Weiss, Heidi L., Anthony, Lowell, Townsend, Courtney M., Evers, B. Mark

Journal:

Gastroenterology

Année:

2012

Langue:

english

Fichier:

PDF, 64 KB

english, 2012

Sa1859 Decreased P85a Expression Contributes to the Loss of Sensitivity to ER Stress in Aged Pancreatic Acinar Cells

Li, Jing, Song, Jun, Campbell, Katherine E., Kim, Ji Tae, Okamura, Daiki, Saito, Hiroshi, Evers, B. Mark

Journal:

Gastroenterology

Année:

2013

Langue:

english

Fichier:

PDF, 60 KB

english, 2013

The homeobox gene CDx-2 is up-regulated in HT-29 cells by PI3-kinase inhibition

Kim, Sunghoon, Murillo, Carlos, Wang, QingDing, Domon-Dell, Claire, Freund, Jean-Noel, Evers, B. Mark

Journal:

Gastroenterology

Année:

2000

Langue:

english

Fichier:

PDF, 213 KB

english, 2000

Inhibition of PI3-K enhances apoptosis of human colon cancer cells treated with sodium butyrate

Wang, QingDing, Kim, Mimi, Li, Nan, Hernandez, Ambrosio, Mark Evers, B.

Journal:

Gastroenterology

Année:

2000

Langue:

english

Fichier:

PDF, 216 KB

english, 2000

Tu1608 Chemical Inhibitors of the Wnt Pathway or G9a Showed Anti-Tumor Effects in Human Neuroendocrine Tumor Cells With Deregulated Wnt/β-Catenin Signaling

Kim, Ji Tae, Li, Jing, Jang, Eun Ryoung, Napier, Dana L., Weiss, Heidi L., Lee, Eun, Townsend, Courtney M., Liu, Chunming, Evers, B. Mark

Journal:

Gastroenterology

Année:

2013

Langue:

english

Fichier:

PDF, 50 KB

english, 2013

Smoking, Physical Activity and Breakfast Consumption Among Secondary School Students in a Southwestern Ontario Community

Bonnie Cohen, Susan Evers, Steve Manske, Kim Bercovitz and H. Gayle Edward

Journal:

Canadian Journal of Public Health / Revue Canadienne de Sante'e Publique

Année:

2003

Langue:

english

Fichier:

PDF, 861 KB

english, 2003

Neurotensin , a novel target of Wnt/β-catenin pathway, promotes growth of neuroendocrine tumor cells

Kim, Ji Tae, Liu, Chunming, Zaytseva, Yekaterina Y., Weiss, Heidi L., Townsend, Courtney M., Evers, B. Mark

Journal:

International Journal of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 436 KB

english, 2015

Deregulation of Wnt/ -catenin signaling through genetic or epigenetic alterations in human neuroendocrine tumors

Kim, J. T., Li, J., Jang, E. R., Gulhati, P., Rychahou, P. G., Napier, D. L., Wang, C., Weiss, H. L., Lee, E. Y., Anthony, L., Townsend, C. M., Liu, C., Evers, B. M.

Journal:

Carcinogenesis

Année:

2013

Langue:

english

Fichier:

PDF, 2.51 MB

english, 2013

Nonclinical Safety Evaluation of Sunitinib: A Potent Inhibitor of VEGF, PDGF, KIT, FLT3, and RET Receptors

Patyna, S., Arrigoni, C., Terron, A., Kim, T.-W., Heward, J. K., Vonderfecht, S. L., Denlinger, R., Turnquist, S. E., Evering, W.

Journal:

Toxicologic Pathology

Année:

2008

Langue:

english

Fichier:

PDF, 678 KB

english, 2008

Cotargeting the PI3K and RAS Pathways for the Treatment of Neuroendocrine Tumors

Valentino, J. D., Li, J., Zaytseva, Y. Y., Mustain, W. C., Elliott, V. A., Kim, J. T., Harris, J. W., Campbell, K., Weiss, H., Wang, C., Song, J., Anthony, L., Townsend, C. M., Evers, B. M.

Journal:

Clinical Cancer Research

Année:

2014

Langue:

english

Fichier:

PDF, 1.99 MB

english, 2014

Tu1908 Differential Expression and Tumorigenic Function of Neurotensin Receptor 1 in Neuroendocrine Tumor Cells

Kim, Ji Tae, Li, Jing, Weiss, Heidi L., Townsend, Courtney M., Evers, B. Mark

Journal:

Gastroenterology

Année:

2015

Langue:

english

Fichier:

PDF, 155 KB

english, 2015

Composite Beam Element with Layerwise Plane Sections

Kim, Youngchan, Davalos, Julio F., Barbero, Ever J.

Journal:

Journal of Engineering Mechanics

Année:

1994

Langue:

english

Fichier:

PDF, 326 KB

english, 1994